Royals vs. White Sox Prediction, Odds, Picks - May 6

Data Skrive

Sean Burke will take the mound for the Chicago White Sox looking to slow down Maikel Garcia and the Kansas City Royals on Tuesday at 7:40 p.m. ET. Oddsmakers list the Royals as -227 favorites on the moneyline, while giving the underdog White Sox +187 moneyline odds to win. Kansas City is the favorite on the run line (-1.5). An 8.5-run total has been set in this matchup.

Take a look at everything you need from a betting perspective on the Royals-White Sox game, regarding the run line, moneyline and total, plus expert picks.

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Royals vs. White Sox Game Information & Odds

When: Tuesday, May 6, 2025 at 7:40 p.m. ET
Where: Kauffman Stadium in Kansas City, Missouri
How to watch on TV: FDSKC and CHSN

Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Royals -227 +187 8.5 -105 -115 -1.5 -109 -111

Royals vs. White Sox Prediction

Score Prediction: Royals 4, White Sox 3
Total Prediction: Under 8.5 runs
Win Probabilities: Royals 58%, White Sox 42%

Royals vs. White Sox Betting Insights

The Royals have been favorites in 13 games this season and won nine (69.2%) of those contests.
Kansas City has played as favorites of -227 or more twice this season and won both games.
Sportsbooks have implied with the moneyline set for this matchup that the Royals have a 69.4% chance to win.
The White Sox have been underdogs in 34 games this season and have come away with the win 10 times (29.4%) in those contests.
This season, Chicago has been victorious three times in 15 chances when named as an underdog of at least +187 or worse on the moneyline.
Oddsmakers have implied with the moneyline set for this matchup that the White Sox have a 34.8% chance of pulling out a win.

Royals Recent Betting Performance

Over the last 10 games, the Royals were named the moneyline favorite by bookmakers just once, a game they won.
Over their last 10 matchups, the Royals and their opponents combined to hit the over three times (all 10 of the games had set totals).
The Royals are 8-2-0 against the spread over their past 10 games.

Royals Recent Stats

Stat Avg/Total Record 8-2 Runs Per Game 4.2 HR 13 ERA 2.12 K/9 7

Royals Player Insights

Bobby Witt Jr. is batting .306 with 13 doubles, four home runs and 14 walks.
Including all MLB hitters, Witt ranks 14th in batting average, 25th in on-base percentage, and 29th in slugging.
Garcia is hitting .319 to pace his team.
Garcia ranks 89th in home runs and 103rd in RBI among all batters in baseball.
Garcia has two straight games with at least one hit. During his last five outings he is batting .550 with two doubles, two home runs, two walks and four RBI.
Vinnie Pasquantino paces the Royals with six home runs and 22 runs batted in.
Pasquantino has at least one base hit in two straight games. During his last five outings he is batting .304 with two doubles, three home runs and six RBI.
Salvador Perez is hitting .244 with 11 doubles, two home runs and seven walks.
Perez takes a five-game streak with at least one hit into this one. During his last five outings he is hitting .400 with three doubles and two RBI.

White Sox Recent Betting Performance

In 10 games as underdogs over the last 10 matchups, the White Sox have a record of 5-5.
When it comes to hitting the over, the White Sox and their opponents are 7-3-0 in their last 10 games with a total.
The White Sox have won seven of their last 10 games against the spread.

White Sox Recent Stats

Stat Avg/Total Record 5-5 Runs Per Game 4.9 HR 9 ERA 3.70 K/9 8.4

White Sox Player Insights

Luis Robert has managed a team-leading five home runs and has driven in 15 runs.
In all of the big leagues, Robert is 57th in home runs and 85th in RBI.
Miguel Vargas has six doubles, two home runs and 14 walks while hitting .220.
Vargas is 180th among all hitters in the majors in homers, and 146th in RBI.
Andrew Benintendi leads the White Sox with five long balls.
Lenyn Sosa leads the White Sox with a team-leading batting average of .256.